Dammarane-Type Triterpenoids from The Stembark of Aglaia argentea (Meliaceae)

Authors

  • Ace Tatang Hidayat Departemen Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Padjadjaran
  • Kindi Farabi Departemen Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Padjadjaran
  • Ida Nur Farida Departemen Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Padjadjaran
  • Kansy Haikal Departemen Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Padjadjaran
  • Nurlelasari Nurlelasari Departemen Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Padjadjaran
  • Desi Harneti Putri Huspa Departemen Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Padjadjaran
  • Rani Maharani Departemen Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Padjadjaran
  • Unang Supratman Departemen Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Padjadjaran
  • Yoshihito Shiono Department of Food, Life, and Environmental Science, Faculty of Agriculture, Yamagata University, Tsuruoka, Yamagata 997-8555, Japan

DOI:

https://doi.org/10.15408/jkv.v4i1.7065

Abstract

Two dammarane-type triterpenoids, 20S,24S-epoxy-3α,25-dihydroxydammarane (1) and 3α-acetyl-20S,24S-epoxy-3α,25-dihydroxydammarane (2), have been isolated from the stembark of Aglaia argentea. The chemical structure of compounds (1 and 2) were identified by spectroscopic evidences including UV, IR, 1D-NMR, 2D-NMR and MS as well as by comparing with previously reported spectral data. Those compounds were isolated from this plant for first time. Compounds (1 and 2) showed cytotoxic activity against P-388 murine leukemia cells with IC50 values of 23.96 and 8.14 mM, respectively.

DOI:http://dx.doi.org/10.15408/jkv.v4i1.7065

Downloads

Download data is not yet available.

Downloads

Additional Files

Published

31-05-2018

Issue

Jurnal Kimia VALENSI Volume 4, No. 1, Mei 2018

Section

Jurnal Kimia VALENSI, Volume 4, No. 1, Mei 2018

How to Cite

Dammarane-Type Triterpenoids from The Stembark of Aglaia argentea (Meliaceae). (2018). Jurnal Kimia Valensi, 4(1), 7-13. https://doi.org/10.15408/jkv.v4i1.7065