Anti-bacterial Activity of Prenylated Xanthone from The Bark of Garcinia lowa

Authors

  • Darwati Darwati Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jalan Raya Bandung-Sumedang Km 21, Jatinangor 45363, Sumedang
  • Elisabeth Krismayanti Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jalan Raya Bandung-Sumedang Km 21, Jatinangor 45363, Sumedang
  • Supriyatna Supriyatna Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Universitas Padjadjaran, Jalan Raya Bandung-Sumedang Km 21, Jatinangor 45363, Sumedang
  • Unang Supratman Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jalan Raya Bandung-Sumedang Km 21, Jatinangor 45363, Sumedang

DOI:

https://doi.org/10.15408/jkv.v2i2.4057

Keywords:

anti-bacterial, Garcinia lowa, mangosharin, prenylated xanthone

Abstract

Bioactivity-guided fractionation of a ethyl acetate extract of Garcinia lowa bark has led to the isolation and identification of a known prenylated xanthone, mangosharin, (2,6-dihydroxy-8-methoxy-5-(3-methylbut-2-enyl)-xanthone (1, 15.4 mg) The structure of the compound was identified from analysis of their spectroscopic data and by comparison with previous studies.Compound 1 showed anti-bacterial activity against Sreptococcus mutans with MIC value of 7.25 mg/mL.

DOI : http://dx.doi.org/10.15408/jkv.v0i0.4057

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Published

30-11-2016

Issue

Jurnal Kimia VALENSI Volume 2, No. 2, November 2016

Section

Jurnal Kimia VALENSI Volume 2, No. 2, November 2016

How to Cite

Anti-bacterial Activity of Prenylated Xanthone from The Bark of Garcinia lowa. (2016). Jurnal Kimia Valensi, 2(2), 81-84. https://doi.org/10.15408/jkv.v2i2.4057