Correlation Between Duration of Using Silicone Oil Tamponade and Increased Intraocular Pressure

Nida Farida, Ghina Fitria Nugraha, Nurmila Sari


Background: Silicone oil is an artificial liquid that functions as a tamponade agent in vitreoretinal surgery. One disadvantage of using silicone oil is that it needs advanced procedures for oil evacuation because it is not absorbed spontaneously by the retina. This evacuation is recommended as soon as the retina heals to prevent complications such as pupil block and glaucoma secondary to silicone oil (SO) emulsification and causing increased intraocular pressure (IOP).  The recommended time for SO evacuation is the first 3-6 months after surgery. The aims of this study is to determine the relationship between increased IOP and duration of use of tamponade SO.

Methods: This study used a cross-sectional design by taking secondary data on retinal detachment history patients who underwent silicone oil evacuation at KMJA Hospital Jakarta from January 2019 to November 2021.

Results: Respondents were 39 patients with an age range of 23-69 years and 71,8% were male. The average duration of use of SO is 9 months. In weeks 3-4 after the SO evacuation, data on the number of eyes with high IOP have obtained from as many as 9 eyes and 6 of them had used tamponade SO for more than 6 months with a p-value of 0.153.

Conclusion: There was no significant association between the duration of SO tamponade use and increased IOP after SO evacuation.


Long use of tamponade SO, increased intraocular pressure, emulsification SO

Full Text:



Astuti W, Kartasasmita A, Dahlan MR. Karakteristik-penggunaan-minyak-silikon-pada-operasi-vitrioretina-di-pusat-mata-nasional-rumah-sakit-mata-cicendo-bandung-periode-januari-desember-2011.Widi-Astuti(1).pdf [Internet]. Bandung: departemen ilmu kesehatan mata fakultas kedokteran universitas padjajaran; 2011. Available from:

Chen Y, Kearns VR, Zhou L, Sandinha T, Lam WC, Steel DH, et al. Silicone oil in vitreoretinal surgery: indications, complications, new developments and alternative long-term tamponade agents. Acta Ophthalmol. 2021 May;99(3):240–50.

Issa R, Xia T, Zarbin MA, Bhagat N. Silicone oil removal: post-operative complications. Eye [Internet]. 2020;34(3):537–43. Available from:


Bowling B. kanski’s clinical ophthalmology a systematic approach. 8 th editi. sydney: Elsevier Inc; 2016.

Toklu Y, Cakmak HB, Ergun SB, Yorgun MA, Simsek S. Time course of silicone oil emulsification. Retina. 2012;32(10):2039–44.

Riedel KG, Gabel VP, Neubauer L, Kampik A, Lund OE. Intravitreal silicone oil injection: complications and treatment of 415 consecutive patients. Graefe’s Arch Clin Exp Ophthalmol = Albr von Graefes Arch fur Klin und Exp Ophthalmol. 1990;228(1):19–23.

Ichhpujani P, Jindal A, Jay Katz L. Silicone oil induced glaucoma: a review. Graefe’s Arch Clin Exp Ophthalmol = Albr von Graefes Arch fur Klin und Exp Ophthalmol. 2009 Dec;247(12):1585–93.

Wickham L, Tranos P, Hiscott P, Charteris D. The use of silicone oil-RMN3 (Oxane HD) as heavier-than-water internal tamponade in complicated inferior retinal detachment surgery. Graefe’s Arch Clin Exp Ophthalmol. 2010;248(9):1225–31.

Abu-Yaghi NE, Abu Gharbieh YA, Al-Amer AM, Alryalat SAS, Nawaiseh MB, Darweesh MJ, et al. Characteristics, fates and complications of long-term silicone oil tamponade after pars plana vitrectomy. BMC Ophthalmol. 2020;20(1):1–7.

Peynian GA, Meffert SA, Conway MD. Vitreoretinal Surgical Techniques. second edi. USA: Informa Health Care; 2007.

Adhi MI, Siyal N. Retinal re-detachments after removal of silicone oil: Frequency and timings in a retrospective clinical study. J Pak Med Assoc. 2019 Dec;69(12):1822–6.

Constantin BD, Andreea M, Andrei B. Anatomical results and complications after silicone oil removal. 2017;61(4):261–6.

Hall john e. Guyton and Hall Textbook of Medical Physiology. 13th editi. philadephia: Elsevier Inc; 2016.

Tortora GJ, Derrickson B. Principles of Anatomy and Physiology. 14th editi. wiley. united states: john wiley & sons, inc; 2014.

Sherwood L. Textbook of Human Physiology. 9th ed. Mandera lidya i, Hartanto H, editors. EGC. jakarta: EGC; 2018.

DOI: Abstract - 0 PDF - 0


  • There are currently no refbacks.

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.


View My Stats