Hubungan Karakteristik Sosiodemografi dengan Hasil Terapi Tuberkulosis Paru di RSUD Banyumas
Abstract
Pulmonary tuberculosis (TB) is one of the infectious diseases caused by Mycobacterium tuberculosis and is one of the highest causes of morbidity and mortality rates with a low level of treatment outcome. Indonesia is the second country in the world with the largest tuberculosis burden. This study aims to determine the relationship of sociodemographic characteristics with the results of pulmonary tuberculosis therapy at Banyumas Regional Public Hospital for the period 2019-2021. This study used a case-control method. The inclusion criteria in this study were new pulmonary tuberculosis patients at the Banyumas Regional Public Hospital and patients aged ≥18 years, both male and female. Multi-drug resistance (MDR) TB patients and patients with incomplete medical record data were excluded. There were 166 patients enrolled in this study. Data analysis was performed by univariate analysis and bivariate analysis by chi-square test. The results showed that the sociodemographic characteristics were dominated by male patients (57,2%), patients aged <65 years (66,3%), patients weighing <55 kg (53%), not graduating from college (94%), currently working (64,5%), married (68,7%), have health insurance (94%), and close distance (<10 km) to the hospital (53%). The conclusion is that gender ((P=0,028; OR 2,112; 95%Cl(1,129 – 3,951)), age (P=0,014; OR 2,413; 95% Cl (1,242 – 4,689)), body weight (P=0,000; OR 3,306; 95%Cl (1,748 – 6,252)), and distance from the patient's house to the hospital (P=0,020; OR 2,190; 95% CI (1,176 – 4,077)) have a significant relationship with the outcome of pulmonary TB therapy at Banyumas Regional Public Hospital.
Keywords
References
Adiputra I. M. S. et al. (2021). Metodologi Penelitian Kesehatan. Yayasan Kita Menulis.
Bakhtiar, M. I., Wiedyaningsih, C., Yasin, N. M., & Kristina, S. A. (2021). Hubungan Karakteristik, Kepatuhan, dan Outcome Klinis Pasien Tuberkulosis Paru Di Puskesmas Kabupaten Bantul. Majalah Farmaseutik, 17(2), 256–269. https://doi.org/10.22146/farmaseutik.v17i2.60681
Chida, N., Ansari, Z., Hussain, H., Jaswal, M., Symes, S., Khan, A. J., & Mohammed, S. (2015). Determinants of default from tuberculosis treatment among patients with drug-susceptible tuberculosis in Karachi, Pakistan: A mixed methods: Study. PLoS ONE, 10(11), 1–14. https://doi.org/10.1371/journal.pone.0142384
Damayanti, D. A., & Hikmah, F. (2017). Analisis Faktor-Faktor yang Mempengaruhi Keberhasilan Pengobatan Pasien Tuberkulosis Paru Studi kasus Rumah Sakit Paru Jember. Prosiding Seminar Rekam Medik Dan Informasi Kesehatan, 119–130.
Dinkes Provinsi Jawa Tengah. (2020). Profil Kesehatan Jawa Tengah Tahun 2019.
Dinkes Provinsi Jawa Tengah. (2021). Profil Kesehatan Jawa Tengah Tahun 2020.
Dujaili, J. A., Sulaiman, S. A. S., Hassali, M. A., Awaisu, A., Blebil, A. Q., & Bredle, J. M. (2015). Health-related quality of life as a predictor of tuberculosis treatment outcomes in Iraq. International Journal of Infectious Diseases, 31(1), 4–8. https://doi.org/10.1016/j.ijid.2014.12.004
El-Shabrawy, M., & El-Shafei, D. A. (2017). Evaluation of treatment failure outcome and its predictors among pulmonary tuberculosis patients in Sharkia Governorate, 2013–2014. Egyptian Journal of Chest Diseases and Tuberculosis, 66(1), 145–152. https://doi.org/10.1016/j.ejcdt.2015.11.002
El Hamdouni, M., Bourkadi, J. E., Benamor, J., Hassar, M., Cherrah, Y., & Ahid, S. (2019). Treatment outcomes of drug resistant tuberculosis patients in Morocco: Multi-centric prospective study. BMC Infectious Diseases, 19(1), 1–7. https://doi.org/10.1186/s12879-019-3931-5
Fitriani, E. (2013). Faktor Resiko Yang Berhubungan Dengan kejadian Tuberkulosis Paru. Unnes Journal of Public Health, 2(1), 2–5. https://doi.org/10.15294/ujph.v2i1.3034
Izudi, J., Tamwesigire, I. K., & Bajunirwe, F. (2020). Treatment success and mortality among adults with tuberculosis in rural eastern Uganda: A retrospective cohort study. BMC Public Health, 20(1), 1–10. https://doi.org/10.1186/s12889-020-08646-0
Javaid, A., Ullah, I., Masud, H., Basit, A., Ahmad, W., Butt, Z. A., & Qasim, M. (2018). Predictors of poor treatment outcomes in multidrug-resistant tuberculosis patients: a retrospective cohort study. Clinical Microbiology and Infection, 24(6), 612–617. https://doi.org/10.1016/j.cmi.2017.09.012
Kant, S., Gupta, H., & Ahluwalia, S. (2015). Significance of Nutrition in Pulmonary Tuberculosis. Critical Reviews in Food Science and Nutrition, 55(7), 955–963. https://doi.org/10.1080/10408398.2012.679500
Kemenkes RI. (2020). Profil Kesehatan Indonesia 2019.
Keng Tok, P. S., Liew, S. M., Wong, L. P., Razali, A., Loganathan, T., Chinna, K., Ismail, N., & Kadir, N. A. (2020). Determinants of unsuccessful treatment outcomes and mortality among tuberculosis patients in Malaysia: A registry-based cohort study. PLoS ONE, 15(4), 1–14. https://doi.org/10.1371/journal.pone.0231986
Khan, A. H., Sulaiman, S. A. S., Hassali, M. A., Khan, K. U., Ming, L. C., Mateen, O., & Ullah, M. O. (2020). Effect of smoking on treatment outcome among tuberculosis patients in Malaysia; A multicenter study. BMC Public Health, 20(1), 1–8. https://doi.org/10.1186/s12889-020-08856-6
Klein, K., Bernachea, M. P., Iribarren, S., Gibbons, L., Chirico, C., & Rubinstein, F. (2019). Erratum: Evaluation of a social protection policy on tuberculosis treatment outcomes: A prospective cohort study (PLoS Med (2019) 16:4 (e1002788) DOI: 10.1371/journal.pmed.1002788). PLoS Medicine, 16(5), 1–16. https://doi.org/10.1371/JOURNAL.PMED.1002826
Kolifarhood, G., Khorasani-Zavareh, D., Salarilak, S., Shoghli, A., & Khosravi, N. (2015). Spatial and non-spatial determinants of successful tuberculosis treatment outcomes: An implication of Geographical Information Systems in health policy-making in a developing country. Journal of Epidemiology and Global Health, 5(3), 221–230. https://doi.org/10.1016/j.jegh.2014.11.001
Lestari, N. P. W. A., Dedy, M. A. E., Artawan, I. M., & Febianti, I. (2022). Perbedaan Usia Dan Jenis Kelamin Terhadap Ketuntasan Pengobatan Tb Paru Di Puskesmas Di Kota Kupang. Cendana Medical Journal, 23(April), 24–31.
Mohidem, N. A., Hashim, Z., Osman, M., Shaharudin, R., Muharam, F. M., & Makeswaran, P. (2018). Demographic, socio-economic and behavior as risk factors of tuberculosis in Malaysia: A systematic review of the literature. Reviews on Environmental Health, 33(4), 407–421. https://doi.org/10.1515/reveh-2018-0026
Mok, J., An, D., Kim, S., Lee, M., Kim, C., & Son, H. (2018). Treatment outcomes and factors affecting treatment outcomes of new patients with tuberculosis in Busan, South Korea: A retrospective study of a citywide registry, 2014-2015. BMC Infectious Diseases, 18(1), 1–9. https://doi.org/10.1186/s12879-018-3574-y
Muchtar, N. H., Herman, D., & Yulistini, Y. (2018). Gambaran Faktor Risiko Timbulnya Tuberkulosis Paru pada Pasien yang Berkunjung ke Unit DOTS RSUP Dr. M. Djamil Padang Tahun 2015. Jurnal Kesehatan Andalas, 7(1), 80. https://doi.org/10.25077/jka.v7i1.783
Namukwaya, E., Nakwagala, F. N., Mulekya, F., Mayanja-Kizza, H., & Mugerwa, R. (2011). Predictors of treatment failure among pulmonary tuberculosis patients in mulago hospital, Uganda. African Health Sciences, 11(SPEC. ISSUE), 105–111. https://doi.org/10.4314/ahs.v11i3.70079
Oktriyedi, F., & Fauta, A. (2021). Analisis kesehatan lingkungan rumah dengan kejadian tuberkulosis di desa tanjung seteko kecamatan indralaya kabupaten ogan ilir. November, 1–12.
Pizzol, D., Veronese, N., Marotta, C., Di Gennaro, F., Moiane, J., Chhaganlal, K., Monno, L., Putoto, G., Mazzucco, W., & Saracino, A. (2018). Predictors of therapy failure in newly diagnosed pulmonary tuberculosis cases in Beira, Mozambique. BMC Research Notes, 11(1), 1–6. https://doi.org/10.1186/s13104-018-3209-9
Pooja Sadana, Singh, T., & SS, D. (2015). Socio-Demographic factors affecting the Treatment Outcome In Patients Of Tuberculosis. National Journal of Community Medicine, 6(4), 609–613.
Restinia M., Khairani S., Manninda R. (2021). Faktor Resiko Penyebab Multidrug Resistant Tuberkulosis: Sistematik Review. Pharmaceutical Biomedical Sciences Journal, 3(1),9-16.
Salam, & Wahyono, T. Y. M. (2020). Pengaruh Jarak ke Fasilitas Pelayanan Kesehatan terhadap Kejadian Default pada Penderita TB Paru di RSUD Goeteng Taroenadibrata Purbalingga. Media Publikasi Promosi Kesehatan Indonesia, 3(3), 197–203.
Saleh Jaber, A. A., Khan, A. H., & Syed Sulaiman, S. A. (2018). Evaluation of tuberculosis defaulters in Yemen from the perspective of health care service. Journal of Pharmaceutical Health Services Research, 9(4), 381–392. https://doi.org/10.1111/jphs.12259
Sari, Y. M., Harahap, J., & Lubis, M. (2020). Faktor Penentu Minat Berkunjung Ulang Pasien Tuberkolosis Di Poliklinik Paru Di Rumah Sakit Pirngadi Di Medan. MPPKI (Media Publikasi Promosi Kesehatan Indonesia): The Indonesian Journal of Health Promotion, 3(1), 67–73. https://jurnal.unismuhpalu.ac.id/index.php/MPPKI/article/view/1030
Sengul, A., Akturk, U. A., Aydemir, Y., Kaya, N., Kocak, N. D., & Tasolar, F. T. (2015). Factors affecting successful treatment outcomes in pulmonary tuberculosis: A single-center experience in Turkey, 2005-2011. Journal of Infection in Developing Countries, 9(8), 821–828. https://doi.org/10.3855/jidc.5925
Shaweno, T., Getnet, M., & Fikru, C. (2020). Does time to loss to follow-up differ among adult tuberculosis patients initiated on tuberculosis treatment and care between general hospital and health centers? A retrospective cohort study. Tropical Medicine and Health, 48(1), 1–11. https://doi.org/10.1186/s41182-020-00198-8
Tesema, T., Seyoum, D., Ejeta, E., & Tsegaye, R. (2020). Determinants of tuberculosis treatment outcome under directly observed treatment short courses in Adama City, Ethiopia. PLoS ONE, 15(4), 1–12. https://doi.org/10.1371/journal.pone.0232468
Thomas, B. E., Thiruvengadam, K., Rani, S., Kadam, D., Ovung, S., Sivakumar, S., Shivakumar, S. V. B. Y., Paradkar, M., Gupte, N., Suryavanshi, N., Dolla, C. K., Gupte, A. N., Kohli, R., Pradhan, N., Sivaramakrishnan, G. N., Gaikwad, S., Kagal, A., Dhanasekaran, K., Deluca, A., … Gupta, A. (2019). Correction: Smoking, alcohol use disorder and tuberculosis treatment outcomes: A dual co-morbidity burden that cannot be ignored (PLoS ONE (2019) 14:7 (e0220507) DOI: 10.1371/journal.pone.0220507). PLoS ONE, 14(11), 1–12. https://doi.org/10.1371/journal.pone.0224914
Tirtana, B. T. (2011). Faktor-Faktor yang Mempengaruhi Keberhasilan Pengobatan Pada Pasien Tuberkulosis Paru dengan Resistensi Obat Tuberkulosis di Wilayah Jawa Tengah. Skripsi, 1–19.
Utami, L. S., & Musyarofah, S. (2021). Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal. Peran Mikronutrisi Sebagai Upaya Pencegahan Covid-19, 11 No 1(Januari), 1–8.
Victoria, M. (2017). Analisis Hubungan Faktor-Faktor yang Mempengaruhi Pengobatan dengan Hasil Pengobatan Pasien Tuberkulosis Paru di Puskesmas Pesantren Kota Kediri. Univeristas Kediri, Jawa Timur.
Wang, X. M., Yin, S. H., Du, J., Du, M. L., Wang, P. Y., Wu, J., Horbinski, C. M., Wu, M. J., Zheng, H. Q., Xu, X. Q., Shu, W., & Zhang, Y. J. (2017). Risk factors for the treatment outcome of retreated pulmonary tuberculosis patients in China: An optimized prediction model. Epidemiology and Infection, 145(9), 1805–1814. https://doi.org/10.1017/S0950268817000656
World Health Organization. (2020). Tuberculosis Report. In Baltimore Health News: Vol. XLIX (Issues 9-10–11).
WHO. (2021). Global Tuberculosis Report 2021. World Health Organization, Geneva.
Wrohan, I., Nguyen, T. A., Nguyen, V. N., Nguyen, B. H., Hoang, T. T. T., Nguyen, P. C., Velen, K., Marks, G. B., & Fox, G. J. (2022). Predictors of treatment outcomes among patients with multidrug-resistant tuberculosis in Vietnam: a retrospective cohort study. BMC Infectious Diseases, 22(1), 1–12. https://doi.org/10.1186/s12879-021-06992-x
Yulisetyaningrum, Y., Hidayah, N., & Yuliarti, R. (2019). Hubungan Jarak Rumah Dengan Kepatuhan Minum Obat Pada Pasien Tbc Di Rsi Sunan Kudus. Jurnal Ilmu Keperawatan Dan Kebidanan, 10(1), 248. https://doi.org/10.26751/jikk.v10i1.676
Zeleke, A., Misiker, B., & Yesuf, T. A. (2020). Drug-induced hepatotoxicity among TB/HIV co-infected patients in a referral hospital, Ethiopia. BMC Research Notes, 13(1), 1–5. https://doi.org/10.1186/s13104-019-4872-1
DOI: 10.15408/pbsj.v5i2.29973
Refbacks
- There are currently no refbacks.
