A New Antiplasmodial Compound from the Papuan Marine Sponge Xestospongia sp.

Murtihapsari Murtihapsari, Amir M Suruwaky, Kadarusman Kadarusman, Dikdik Kurnia, Tati Herlina, Unang Supratman

Abstract


A new antiplasmodial compound, 2-(3H-diazirine-3-yl)benzaldehyde (1), has been isolated from the Papuan marine sponge Xestospongia sp. The structure elucidation of compound 1 was determined by spectroscopic evidences including UV, IR, MS, 1D and 2D-NMR analysis. Compound 1 showed moderate antiplasmodial activity against Plasmodium falciparum with IC50 value of 1.08 x 10-6 mM.

DOI:http://dx.doi.org/10.15408/jkv.v4i1.6735


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DOI: https://doi.org/10.15408/jkv.v4i1.6735 Abstract - 0 PDF - 0

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Copyright (c) 2019 Murtihapsari Murtihapsari, Amir M Suruwaky, Kadarusman Kadarusman, Dikdik Kurnia, Tati Herlina, Unang Supratman

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Penerbit: Program Studi Kimia, Fakultas Sains dan Teknologi, UIN Syarif Hidayatullah Jakarta.Jl. Ir. H. Juanda No. 95, Ciputat, Jakarta 15412, Indonesia, Telp. 021-7492855, Fax. 021-7493351, website: http://journal.uinjkt.ac.id/index.php/valensi, e-mail: kimia@uinjkt.ac.idISSN: 2460-6065, E-ISSN: 2548-3013 // ]]>

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