Formulation and Antioxidant Evaluation of Clay Masks Containing Robusta Coffee Pulp Extract

Authors

  • Fith Khaira Nursal Department of Pharmaceutics, Magister of Pharmaceutical Science, School of Postgraduate, Universitas Muhammadiyah Prof. DR. HAMKA Jl. Warung Buncit Raya No.17, Jakarta Selatan, Indonesia, 12740 https://orcid.org/0000-0002-7673-3775
  • Anisa Amalia Department of Pharmaceutis, Faculty of Pharmacy and Science, Universitas Muhammadiyah Prof. DR. HAMKA, Jl. Delima II/IV, Jakarta Timur, Indonesia 13460 https://orcid.org/0000-0002-3631-4090
  • Karsiti Karsiti Pharmacy Study Programe, Faculty of Pharmacy and Science, Universitas Muhammadiyah Prof. DR. HAMKA, Jl. Delima II/IV, Jakarta Timur, Indonesia 13460
  • Sri Nevi Gantini .Pharmacy Study Programe, Faculty of Pharmacy and Science, Universitas Muhammadiyah Prof. DR. HAMKA, Jl. Delima II/IV, Jakarta Timur, Indonesia 13460

DOI:

https://doi.org/10.15408/pbsj.v7i2.47124

Keywords:

antioxidants, clay mask, coffee bean pulp, formulation, physical properties

Abstract

The pulp of robusta coffee (Coffea canephora L.) is known to contain chlorogenic acid compounds that have potential as antioxidants. The content of this compound can be utilized as an active ingredient in cosmetics such as clay masks. The main component that affects the physical properties of a clay mask is the clay base. This study aims to develop a clay mask formulation from robusta coffee pulp extract with variations in the concentration of base combinations, namely bentonite and kaolin, and to observe their effects on the physical properties of the dosage form. The base concentration variations used were 20% (F1), 25% (F2), and 30% (F3) with a bentonite to kaolin ratio of 1:2. The evaluation of physical properties included organoleptic tests, homogeneity tests, pH tests, spreadability tests, adhesion tests, viscosity tests, and drying time measurements. The evaluation results showed that all clay masks were homogeneous with pH values ranging from 5.15 ± 0.04 to 5.29 ± 0.12, spreadability values of 4.60 ± 0.22 to 4.74 ± 0.37 cm, adhesion values of 0.82 ± 0.11 to 1.16 ± 0.15 seconds, and viscosity ranged from 5501 ± 670.22 to 7567.67 ± 220.30 mPa.s, and drying time ranged from 20.60 ± 0.39 to 25.34 ± 0.80 minutes. Results of the antioxidant activity test indicated that the clay mask made from robusta coffee pulp extract is a powerful antioxidant with IC50 values of 28.31 ± 4.72 to 30.45 ± 5.69 ppm. Variations in the concentration of the clay mask base significantly (p < 0.05) affected the viscosity and drying time of the dosage form. In summary, the clay mask formulations satisfied the essential physical criteria and showed promise for cosmetic application. F3 emerged as the leading formula, exhibiting the highest antioxidant capacity, evidenced by its lowest IC₅₀ value.

References

Amalia, A., Elfiyani, R., Chenia, A., 2021. Peningkatan Laju Difusi Alisin dalam Sistem Fitosom Ekstrak Bawang Putih. J. Ilmu Kefarmasian Indones. 19, 1–8. https://doi.org/10.35814/jifi.v19i1.842

Ardhany, S.D., Kusumawardhani, E., Suling, C.A., Dzuary, F.H., Novaryatiin, S., 2022. Clay Mask Papilak (Mussaenda frondosa L.) terhadap Bakteri Penyebab Acne Vulgaris. Lumbung Farm. J. Ilmu Kefarmasian 3, 110–117.

Bawekes, S.M., Yudistira, A., Rumondor, E.M., 2023. Uji Kualitatif Kandungan Senyawa Kimia Perasan Jeruk Nipis (Citrus aurantifolia Swingle). Pharmacon 12, 373–377. https://doi.org/10.35799/pha.12.2023.49269

Dipahayu, D., Lestari, K.A.P., 2021. Evaluasi Fisik Masker Anti Jerawat Dengan Ekstrak Etanol Daun Ubi Jalar Ungu (Ipomoea batatas (L.) Varietas Antin-3. J. Pharmasci (Journal Pharm. Sci. 6, 69–73. https://doi.org/10.53342/pharmasci.v6i2.219

Elfiyani, R., Nursal, F., Deviyolanda, R., Shifa, S., 2023. Pemanfaatan Ekstrak Kulit Putih Semangka dalam Sediaan Masker Clay. J. Sains Farm. Klin. 10, 218–225. https://doi.org/10.25077/jsfk.10.2.218-225.2023

Fauziah, F., Alvanny, N., Andalia, K., 2022. Formulasi dan Evaluasi Masker Clay Anti Jerawat dari Ekstrak Etanol Daun Pepaya (Carica Papaya L.). J. Ris. Kefarmasian Indones. 4, 306–320. https://doi.org/10.33759/jrki.v4i3.283

Febriani, Y., Sembiring, R., 2021. Formulation and Antioxidant Activity of Clay Mask of Ethanol Extract Tamarillo (Solanum betaceum Cav.). Indones. J. Pharm. Sci. Technol. Supp 1, 22–30. https://doi.org/10.24198/ijpst.v1i1.36432

Harahap, M.R., 2017. Identifikasi Daging Buah Kopi Robusta (Coffea robusta) Berasal Dari Provinsi Aceh. Elkawnie J. Islam. Sci. Technol. 3, 201–210. https://doi.org/10.22373/ekw.v3i2.2770

Indriastuti, D., Dewi, M.L., Priani, S.E., 2022. Literature Review Formulasi Sediaan Masker Clay Antioksidan. Bandung Conf. Ser. Pharm. 2, 1129–1135. https://doi.org/10.29313/bcsp.v2i2.4850

Jami’ah, S.R., Ifaya, M., Pusmarani, J., Nurhikma, E., 2018. Uji Aktivitas Antioksidan Ekstrak Metanol Kulit Pisang Raja (Musa Paradisiaca sapientum) dengan Metode DPPH (2,2-Difenil-1-Pikrilhidrazil). J. Mandala Pharmacon Indones. 4, 33–38. https://doi.org/10.35311/jmpi.v4i1.22

Kemenkes RI, 2017. Farmakope Herbal Indonesia Edisi 2. Kementrian Kesehatan Republik Indonesia.

Krismayadi, K., Halimatushadyah, E., Apriani, D., Cahyani, M.F., 2024. Standarisasi Mutu Simplisia dan Ekstrak Etanol Daun Kemangi (Ocimum x afriacanum Lour.). Pharm. Genius 03, 67–81. https://doi.org/10.56359/pharmgen.v3i2.333

Kumalasari, E., Wulandari, R.A., Aisyah, N., Febrianti, D.R., Niah, R., 2023. Formulasi Sediaan Masker Clay dari Ekstrak Daun Pidada Merah (Sonneratia caseolaris) sebagai Antioksidan. J. Insa. Farm. Indones. 6, 55–64. https://doi.org/10.36387/jifi.v6i1.1363

Nugrahaeni, F., Amalia, A., Rohmah, F., 2025. Formulation of Facial Clay Mask from Red Glutinous Rice (Oryza sativa L. var. glutinosa) Bran Extract. Trop. J. Nat. Prod. Res. 9, 1996–2001. https://doi.org/10.26538/tjnpr/v9i5.17

Nursal, F.K., Amalia, A., Nining, N., Putri, D.A., Larasati, K.D., 2024. Development of Coffee Fruit Skin (Coffea canephora) formula as Antioxidant peel-off Masks. J. Sains Farm. Klin. 11, 118–126. https://doi.org/10.25077/jsfk.11.2.118-126.2024

Saerang, M.F., Jaya Edy, H., Siampa, P., 2023. Formulasi Sediaan Krim dengan Ekstrak Etanol Daun Gedi Hijau (Abelmoschus manihot L.) terhadap Propionibacterium acnes. Pharmacon 12, 350–357. https://doi.org/10.35799/pha.12.2023.49075

Shahidi, F., Ambigaipalan, P., 2015. Phenolics and polyphenolics in foods, beverages and spices: Antioxidant activity and health effects - A review. J. Funct. Foods 18, 820–897. https://doi.org/10.1016/j.jff.2015.06.018

Shakeel, A., Kirichek, A., Chassagne, C., 2021. Applied Clay Science Rheology and yielding transitions in mixed kaolinite / bentonite suspensions. Appl. Clay Sci. 211, 106206. https://doi.org/10.1016/j.clay.2021.106206

Syamsidi, A., Syamsuddin, A.M., Sulastri, E., 2021. Formulation and Antioxidant Activity of Clay Mask of Tomato ( Solanum lycopersicum L .) Lycopene Extract with Variation of Concentration of Kaoline and Bentonite Bases ). J. Farm. Galen. (Galenika J. Pharmacy) 7, 77–90. https://doi.org/10.22487/j24428744.2021.v7.i1.15462

Tungadi, R., Thomas, N.A., Paneo, M.A., Monoarfa, R.P., 2024. Formulasi dan Evaluasi Sediaan Masker Lumpur Ekstrak Bunga Rosella (Hibiscus Sabdariffa L.) menggunakan Basis Bentonit dan Kaolin. Indones. J. Pharm. Educ. 4, 336–345. https://doi.org/10.37311/ijpe.v4i2.18040

Widyaningrum, N., Murrukmihadi, M., Ekawati, S.K., 2012. Pengaruh Konsentrasi Ekstrak Etanolik Daun Teh Hijau (Camellia sinesis L.) dalam Sediaan Krim terhadap Sifat Fisik dan Aktivitas Antibakteri. Sains Med. J. Kedokt. dan Kesehat. 4, 147–156. https://doi.org/10.30659/sainsmed.v4i2.371

Winahyu, D.A., Marcellia, S., Diatri, M.I., 2021. Uji Aktivitas Antioksidan Ekstrak Kulit Buah Kopi Robusta (Coffea canephora Pierre ex A.Foehner) dalam Sediaan Krim. J. Farm. Malahayati 4, 82–92. https://doi.org/10.33024/jfm.v4i1.4470

Wulan, W., Yudistira, A., Rotinsulu, H., 2019. Uji Aktivitas Antioksidan Dari Ekstrak Etanol Daun Mimosa pudica Linn. Menggunakan Metode DPPH. Pharmacon 8, 106–113. https://doi.org/10.35799/pha.8.2019.29243

Yasir, A.S., Ade, M.U., Hamid Al Fikri, A., 2023. Aktivitas Antioksidan dari Kulit Ari Biji Kopi Robusta (Coffea canephora) dalam Formulasi Sediaan Gel. J. Farmagazine X, 50–56. https://doi.org/10.47653/farm.v10i1.643

Zainal, T.H., Ulfa, M., Nisa, M., Pawarrangan, T.J., 2023. Formulasi Masker Clay Ekstrak Kulit Buah Pisang Muli (Musa acuminata L.). J. Penelit. Farm. Indones. 12, 7–12. https://doi.org/10.51887/jpfi.v12i1.1760

Zhang, X., Zhang, Z., Tao, H., He, X., Hsu, K., Wang, W., Fang, X., Steel, A., 2023. Comprehensive assessment of the efficacy and safety of a clay mask in oily and acne skin. Ski. Res. Technol. 29, 13513. https://doi.org/10.1111/srt.13513

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Published

2025-12-31

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How to Cite

Formulation and Antioxidant Evaluation of Clay Masks Containing Robusta Coffee Pulp Extract. (2025). Pharmaceutical and Biomedical Sciences Journal (PBSJ), 7(2), 211-220. https://doi.org/10.15408/pbsj.v7i2.47124