Tanaman Genetically Modified Organism (GMO) dan Perspektif Hukumnya di Indonesia

Yuwono Prianto, Swara Yudhasasmita

Abstract


Abstrak

Genetically modified organism (GMO) merupakan organisme yang gen-gennya telah diubah dengan menggunakan teknik rekayasa genetika. Produk rekayasa genetika diklasifikasikan menjadi 4 macam, yaitu generasi pertama: satu sifat; generasi kedua: kumpulan sifat; generasi ketiga dan keempat: near-intragenic, intragenic, dan cisgenic. Adapun produk rekayasa genetika pada tanaman di Indonesia di antaranya adalah padi, tomat, tebu, singkong, dan kentang. Regulasi tanaman hasil rekayasa genetika diatur oleh beberapa lembaga, di antaranya Kementerian Lingkungan Hidup, Kementerian Pertanian, Komisi Keamanan Hayati, Tim Teknis Keamanan Hayati, dan Biosafety Clearing House, berdasarkan peraturan pemerintah No. 21 tahun 2005. Pengujian yang dilakukan pada produk rekayasa genetika meliputi analisis sumber gen penyebab alergi, sekuens homolog asam amino, resistensi pepsin, skrining serum, serta penggunaan hewan uji. Berbagai produk GMO di Indonesia sejauh ini merupakan produk yang dibutuhkan dalam memenuhi kebutuhan hidup sehari-hari, yang perlu diawasi secara ketat dari segi dampaknya terhadap lingkungan melalui ketentuan hukum yang berlaku, yang diwakili oleh instansi-instansi terkait tersebut.

Abstract

Genetically modified organism (GMO) is an organism whose genes that have been altered by using genetic engineering techniques. Genetic engineering products are classified into 4 types, which are the first generation: one trait; the second generation: a collection of properties; the third and fourth generation: near-intragenic, intragenic, and cisgenic. The genetic engineering products in plants in Indonesia include rice, tomatoes, sugar cane, cassava, and potatoes. The application of the genetically engineered crops is regulated by several institutions, including the Ministry of Environment, the Ministry of Agriculture, the Biosafety Commission, the Biosafety Technical Team and the Biosafety Clearing House, under government regulation No. 21 of the year 2005. Assessment for GMO product can be conducted by analyzing the source of an allergic gene, sequence homology of amino acid, resistance to pepsin, serum screening and use of an animal model. The GMO products in Indonesia are required so far to meet the needs of daily use, which need to be closely monitored in terms of their impact on the environment through the legal provisions, represented by the respective agencies.

 


Keywords


Kata kunci: GMO; Hukum Indonesia; Regulasi; Tanaman; Keywords: GMO; Indonesian Law; Plant; Regulation

Full Text:

PDF

References


REFERENSI

Aalberse, R. C. (2005). Assessment of sequence homology and cross-reactivity. Toxicology and Applied Pharmacology, 207(2 Suppl), 149–151. http://doi.org/10.1016/j.taap.2005.01.021

Altschul, S. F., Madden, T. L., Schaffer, A. A., Zhang, J., Zhang, Z., Miller, W., & Lipman, D. J. (1997). Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Research, 25(17), 3389–3402.

Arora, N., & Mishra, A. (2011). Safety assessment of genetically modified food crops. Allergy Asthma Immunology, 25(2), 53–60.

De Jaramillo, E. H. (2009). Biosafety of genetically modified organisms: basic concepts, methods and issues. (M. Khalequzzaman A. Chowdhury, M. I. Hoque, & A. Sonnino, Eds.). Rome, Italy: FAO.

FAO & WHO. (2001). Joint FAO/WHO expert consultation on allergenicity of foods derived from biotechnology. Biotechnology. Rome, Italy: FAO & WHO.

FAO, WHO, & Codex Alimentarius Commission. (2003). The third session of the codex ad hoc intergovernmental task force on foods derived from biotechnology. Rome, Italy.

Fiers, M. W. E. J., Kleter, G. a, Nijland, H., Peijnenburg, A. a C. M., Nap, J. P., & van Ham, R. C. H. J. (2004). Allermatch, a webtool for the prediction of potential allergenicity according to current FAO/WHO Codex alimentarius guidelines. BMC Bioinformatics, 5, 133. http://doi.org/10.1186/1471-2105-5-133

Han, P., Niu, C. Y., Lei, C. L., Cui, J. J., & Desneux, N. (2010). Quantification of toxins in a Cry1Ac + CpTI cotton cultivar and its potential effects on the honey bee Apis mellifera L. Ecotoxicology, 19(8), 1452–1459. http://doi.org/10.1007/s10646-010-0530-z

Hariadi, A. (2001). Pemanfaatan bioteknologi dalam bidang kesehatan. Jakarta, Indonesia: BPHN-Departemen Kehakiman dan Hak Asasi Manusia Republik Indonesia.

Indonesia Biosafety Clearing House. (2012). Peraturan perundangan produk rekayasa genetika.

Ishak, I. I. (2004). Pengesahan Cartagena protocol on biosafety to the convention on biological diversity.

Ivanciuc, O., Schein, C. H., & Braun, W. (2003). SDAP: database and computational tools for allergenic proteins. Nucleic Acids Research, 31(1), 359–362.

Kementrian Pertahanan Republik Indonesia. (2015). Buku putih pertahanan Indonesia. Jakarta, Indonesia: Kementrian Pertahanan Republik Indonesia.

Kranti, K. . (2012). Bt cotton Q & A. Mumbai: Indian Society For Cotton Improvement.

Lang, A., & Vojtech, E. (2006). The effects of pollen consumption of transgenic Bt maize on the common swallowtail, Papilio machaon L. (Lepidoptera, Papilionidae). Basic and Applied Ecology, 7(4), 296–306. http://doi.org/10.1016/j.baae.2005.10.003

Li, S. X., Chen, L. H., Zheng, F. Y., & Li, Y. C. (2013). Effect of the cp4-epsps gene on metal bioavailability in maize and soybean using bionic gastrointestinal tracts and ICP-MS determination. Journal of Agricultural and Food Chemistry, 61(7), 1579–1584. http://doi.org/10.1021/jf303962a

Lin, C. H., & Pan, T. M. (2016). Perspectives on genetically modified crops and food detection. Journal of Food and Drug Analysis, 24(1), 1–8. http://doi.org/10.1016/j.jfda.2015.06.011

Losey, J. E., Rayor, L. S., & Carter, M. E. (1999). Transgenic pollen harms monarch larvae. Nature, 399(May), 214–215.

Lu, I.-J., Lin, C.-H., & Pan, T.-M. (2010). Establishment of a system based on universal multiplex-PCR for screening genetically modified crops. Analytical and Bioanalytical Chemistry, 396(6), 2055–2064. http://doi.org/10.1007/s00216-009-3214-x

Mahkamah Konstitusi Republik Indonesia. (2012). Putusan Nomor 99/PUU-X/2012. Jakarta, Indonesia. Retrieved from https://www.spi.or.id/wp-content/uploads/2014/11/putusan_sidang_99-PUU-2012-tanaman-telah-ucap-18-Juli-2013.pdf

Mattila, H. R., Sears, M. K., & Duan, J. J. (2005). Response of Danaus plexippus to pollen of two new Bt corn events via laboratory bioassay. Entomologia Experimentalis et Applicata, 116(1), 31–41. http://doi.org/10.1111/j.1570-7458.2005.00304.x

McClain, S., & Bannon, G. A. (2006). Animal models of food allergy: opportunities and barriers. Current Allergy and Asthma Reports, 6(2), 141–144.

Mudzakir. (2013). Pengkajian hukum tentang ketentuan pidana dalam penerapan bioteknologi kesehatan. Jakarta, Indonesia: BPHN-Departemen Kehakiman dan Hak Asasi Manusia Republik Indonesia.

Nakamura, R., Teshima, R., Takagi, K., & Sawada, J. (2005). Development of allergen database for food safety (adfs): an integrated database to search allergens and predict allergenicity. Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences, 123, 32–36.

Natarajan, S., Luthria, D., Bae, H., Lakshman, D., & Mitra, A. (2013). Transgenic soybeans and soybean protein analysis: An overview. Journal of Agricultural and Food Chemistry, 61(48), 11736–11743. http://doi.org/10.1021/jf402148e

Pearson, W. R., & Lipman, D. J. (1988). Improved tools for biological sequence comparison. Proceedings of the National Academy of Sciences of the United States of America, 85(8), 2444–2448.

Perry, J. N., Devos, Y., Arpaia, S., Bartsch, D., Gathmann, A., Hails, R. S., … Sweet, J. B. (2010). A mathematical model of exposure of nontarget Lepidoptera to Bt-maize pollen expressing Cry1Ab within Europe. Proceedings of the Royal Society B-Biological Sciences, 277(1686), 1417–1425.http://doi.org/DOI10.1098/rspb.2009.2091

Prasifka, P. L., Hellmich, R. L., Prasifka, J. R., & Lewis, L. C. (2007). Effects of Cry1Ab-expressing corn anthers on the movement of monarch butterfly larvae. Environmental Entomology, 36(1), 228–233.

Rahayu, T. (2015). Indonesia agricultural biotechnology annual. Indonesia.

Saha, S., & Raghava, G. P. S. (2006). AlgPred: Prediction of allergenic proteins and mapping of IgE epitopes. Nucleic Acids Research, 34, 202–209. http://doi.org/10.1093/nar/gkl343

Takano-Kai, N., Jiang, H., Kubo, T., Sweeney, M., Matsumoto, T., Kanamori, H., … McCouch, S. (2009). Evolutionary history of GS3, a gene conferring grain length in rice. Genetics, 182(4), 1323–1334. http://doi.org/10.1534/genetics.109.103002

Wright, T., & Rahmanulloh, A. (2016). Oilseeds and Products annual report 2017. Indonesia.

Xue, K., Yang, J., Liu, B., & Xue, D. (2012). The integrated risk assessment of transgenic rice Oryza sativa: A comparative proteomics approach. Food Chemistry, 135(1), 314–318. http://doi.org/10.1016/j.foodchem.2012.04.042




DOI: https://doi.org/10.15408/kauniyah.v10i2.5264 Abstract - 0 PDF - 0

Refbacks

  • There are currently no refbacks.


This work is licensed under a CC-BY- SA.

Indexed By:

/public/site/images/rachma/logo_moraref_75 /public/site/images/rachma/logo_google_scholar_75_01 /public/site/images/rachma/logo_isjd_120 /public/site/images/rachma/logo_garuda_75 /public/site/images/rachma/logo_crossref_120/public/site/images/rachma/logo_base_2_120 /public/site/images/rachma/neliti-blue_75   /public/site/images/rachma/dimensions-logo_120