Measuring Compliance Therapy in Type 2 Diabetes Mellitus Patients using Proportion of Days Covered (PDC) Method and Its Effect on Clinical Outcomes

Irvan - Anwar; Sabarudin Sabarudin; Rachma Malina; Ayu Dewi Widaningsih; Aurelia Arbaleta Wijaya; Lilis Nurawaliah

Measuring Compliance Therapy in Type 2 Diabetes Mellitus Patients using Proportion of Days Covered (PDC) Method and Its Effect on Clinical Outcomes

Irvan - Anwar, Sabarudin Sabarudin, Rachma Malina, Ayu Dewi Widaningsih, Aurelia Arbaleta Wijaya, Lilis Nurawaliah

Abstract

Diabetes Mellitus (DM) is a chronic disease that occurs when blood glucose levels rise beyond normal limits because the body is unable to produce or use insulin effectively. Therapeutic adherence is one of the causes of normal blood glucose levels and the success of patient therapy. Measurement of therapeutic adherence of dm type 2 patients needs to be carried out to monitor the success of their therapy. This study aims to determine the adherence of antidiabetic therapy using the Proportion of Days Covered (PDC) method and its effect on the clinical outcomes of type 2 DM patients at Sulawesi Tenggara. The research method used is observational research with a descriptive design approach. The sample of this study was 186 people obtained using the Slovin formula. Patients are said to be adherence if their PDC value ≥ 80% and are said to be non-adherence if their PDC value < 80%. The data were analyzed using the chi square test. The results showed that patients adhering to treatment amounted to 130 people (69.9%), while patients who did not comply with treatment amounted to 56 people (30,1%) and there was a significant influence between adherence to antidiabetic therapy on the success of therapy (clinical outcome) with p value = 0.000 in type 2 DM patients at Sulawesi Tenggara. It was be concluded that most of the patients in this study were adherent to the treatment and there was a significant influence between the adherence of antidiabetic therapy to the success of the therapy (clinical outcomes)

Keywords

diabetes mellitus, adherence therapy, success therapy, chi square, PDC

References

Adikusuma, W. and Qiyaam, N. (2017) ‘ANTIDIABETIK ORAL TERHADAP KADAR HEMOGLOBIN TERGLIKASI ( HbA 1 c ) PADA PASIEN DIABETES MELITUS’, Jurnal Ilmiah Ibnu Sina, 2(2), pp. 279–286.

Almira, N., Arifin, S. and Rosida, L. (2019) ‘Faktor-Faktor yang Berhubungan dengan Perilaku Kepatuhan Minum Obat Anti Diabetes pada Penderita Diabetes Mellitus Tipe 2 di Puskesmas Teluk Dalam Banjarmasin’, Homeostasis, 2(1), pp. 9–12.

Astuti and Purnama, A. (2018) ‘Membaca Al-Quran Dapat Menurunkan Kadar Glukosa Darah pada Pasien Diabetes’, Jurnal Keperawatan, 000(99), pp. 479–486.

Atmaja, M. A., Diani, N. and Rahmayanti, D. (2017) ‘Evaluasi Cara Penggunaan Injeksi Insulin Pen Pada Penderita Diabetes Mellitus Di Rsud Ulin Banjarmasin’, Dunia Keperawatan, 5(1), p. 37. doi: 10.20527/dk.v5i1.3639.

Bell, K. F. et al. (2017) ‘Comparing Medication Adherence Glucose Cotransporter 2 Inhibitors with Type 2 Diabetes Using Sodium- and Persistence Among Patients or Sulfonylureas’, (June), pp. 165–174.

Bulu, A., Wahyuni, T. D. and Sutriningsih, A. (2019) ‘Hubungan Antara Tingkat Kepatuhan Minum Obat Dengan Kadar Gula Darah Pada Pasien Diabetes Melitus Tipe II’, Ilmiah Keperawatan, 4(1), pp. 181–189.

Carola, H. et al. (2016) ‘One-year Adherence to Oral Antihyperglycemic Medication and Risk Prediction of Patient Outcomes for Adults with Diabetes Melitus’, Medicine, 95(26).

Delvechia Agustin, L., Noor Istiqomah, I. and Mashuri (2022) ‘Manajemen Kadar Glukosa Darah Pasien Diabetes Mellitus Tipe 2 Melalui Puasa Ramadhan : Literatur Review’, Jurnal Kesehatan Komunitas Indonesia, 2(1), pp. 78–91. Available at: https://ebsina.or.id/journals/index.php/jkki.

Dewi, E. U. (2015) ‘Gambaran Faktor-Faktor Yang Mempengaruhi Terkendalinya Kadar Gula Darah Pada Pasien Diabetes Mellitus Di Puskesmas Pakis Surabaya’, Jurnal Keperawatan, 4(2). doi: 10.47560/kep.v4i2.143.

Febriyani, D. et al. (2021) ‘Profil Terapi Antidiabetes Oral Pada Pasien Diabetes Mellitus Tipe II Di Instalasi Rawat Jalan Rumah Sakit Anwar Medika’, Journal of Pharmaceutical Care Anwar Medika, 3(2), pp. 137–150. doi: 10.36932/jpcam.v3i2.71.

Gayatri, R. W. (2019) ‘Hubungan Faktor Riwayat Diabetes Mellitus Dan Kadar Gula Darah Puasa Dengan Kejadian Diabetes Mellitus Tipe 2 Pada Pasien Usia 25-64 Tahun Di Puskesmas Kendal Kerep Kota Malang’, Preventia : The Indonesian Journal of Public Health, 4(1), p. 56. doi: 10.17977/um044v4i1p56-62.

Hamarno, R., Nurdiansyah Z, M. and Toyibah, A. (2016) ‘HUBUNGAN ANTARA KEPATUHAN KONTROL DENGAN TERJADINYA KOMPLIKASI KRONIS PADA PENDERITA DIABETES MELITUS TIPE 2 DI PUSKESMAS JANTI KOTA MALANG Correlation on the compliance control with the chronic complication among diabetes mellitus type 2 at the Janti Com’, Ejournal.Umm.Ac.Id, 7(2), pp. 126–134. Available at: http://ejournal.umm.ac.id/index.php/keperawatan/issue/view.

Horii, T. et al. (2019) ‘Determination of factors affecting medication adherence in type 2 diabetes mellitus patients using a nationwide claim-based database in Japan’, PLoS ONE, 14(10), pp. 1–12. doi: 10.1371/journal.pone.0223431.

Lin, L. K. et al. (2017) ‘Medication adherence and glycemic control among newly diagnosed diabetes patients’, BMJ Open Diabetes Research and Care, 5(1), pp. 1–9. doi: 10.1136/bmjdrc-2017-000429.

Masruroh, E.- (2018) ‘Hubungan Umur Dan Status Gizi Dengan Kadar Gula Darah Penderita Diabetes Melitus Tipe Ii’, Jurnal Ilmu Kesehatan, 6(2), p. 153. doi: 10.32831/jik.v6i2.172.

Meta Srikartika, V., Akbar, M. R. and Nautika Lingga, H. (2019) ‘Evaluasi Intervensi Media Booklet Terhadap Tingkat Pengetahuan Dan Kepatuhan Pasien Diabetes Melitus Tipe 2 Di Puskesmas Banjarbaru Selatan’, Jurnal Publikasi Kesehatan Masyarakat Indonesia, 6(1), pp. 27–35. doi: 10.20527/jpkmi.v6i1.6874.

Milita, F., Handayani, S. and Setiaji, B. (2021) ‘Kejadian Diabetes Mellitus Tipe II pada Lanjut Usia di Indonesia (Analisis Riskesdas 2018)’, Jurnal Kedokteran dan Kesehatan, 17(1), p. 9. doi: 10.24853/jkk.17.1.9-20.

Ningrum, D. K. (2017) ‘Kepatuhan Minum Obat pada Penderita Diabetes MElitus Tipe II’, Higeia Journal of Public Health Research and Development, 1(3), pp. 84–94.

PERKENI (2021) Pedoman Pengelolaan dan Pencegahan Diabetes Melitus Tipe 2 Dewasa di Indonesia 2021, Pb Perkeni. Available at: www.ginasthma.org.

Prieto-Merino, D. et al. (2021) ‘Estimating proportion of days covered (PDC) using real-world online medicine suppliers’ datasets’, Journal of Pharmaceutical Policy and Practice, 14(1), pp. 1–14. doi: 10.1186/s40545-021-00385-w.

Rasmussen, J. B. et al. (2014) ‘Random blood glucose may be used to assess long-term glycaemic control among patients with type 2 diabetes mellitus in a rural African clinical setting’, Tropical Medicine and International Health, 19(12), pp. 1515–1519. doi: 10.1111/tmi.12391.

Soraya, I. A. et al. (2022) ‘The Association between Adherence to Oral Antihyperglycemic Agent and HbA1c Level’, Pharmaceutical Sciences and Research, 9(2), pp. 93–101. doi: 10.7454/psr.v9i2.1260.

Swe, K. and Reddy, S. S. K. (2020) ‘Improving Adherence in Type 2 Diabetes’, Clinics in Geriatric Medicine, 36(3), pp. 477–489. doi: 10.1016/j.cger.2020.04.007.

Yanto, A. and Setyawati, D. (2017) ‘Dukungan Keluarga Pada Pasien Diabetes Mellitus Tipe 2 Di Kota Semarang’, (September), pp. 45–49.

Full Text: PDF

DOI: 10.15408/pbsj.v6i1.37761